GLP-1 weight care
Semaglutide (Wegovy®) for weight management
Medical review pending · Last updated
Semaglutide is a once-weekly injectable (and now once-daily oral) GLP-1 medicine. If prescribed by a licensed provider, it is used with a reduced-calorie diet and increased physical activity.
FDA-approved uses of Wegovy®
- Chronic weight management in adults with obesity, or overweight with at least one weight-related condition, and in pediatric patients 12 and older with obesity (injection).
- Reducing the risk of major cardiovascular events in adults with established cardiovascular disease and obesity or overweight.
- Noncirrhotic MASH (metabolic dysfunction-associated steatohepatitis) with moderate-to-advanced liver fibrosis in adults, with diet and exercise.
How semaglutide works
Semaglutide activates GLP-1 receptors, slowing stomach emptying and signaling fullness in the brain. Doses are typically increased gradually over several months to help with tolerability, following the FDA-approved label.
What to expect
Results vary from person to person, and no specific amount of weight loss can be promised. Gastrointestinal side effects are common, especially as the dose increases. Your provider will review your goals, history, and follow-up plan.
Cost
Cost depends on insurance coverage and manufacturer self-pay programs, which change frequently.
Compare: tirzepatide (Zepbound®) · tirzepatide vs. semaglutide · Zepbound vs. Wegovy
Frequently asked questions
What is the difference between Wegovy and Ozempic?
Both contain semaglutide. Wegovy is FDA-approved for chronic weight management (and cardiovascular risk reduction and MASH in certain adults); Ozempic is approved for type 2 diabetes. They have different dosing.
Is there a semaglutide pill for weight loss?
Yes. FDA approved a once-daily oral Wegovy® tablet for chronic weight management in December 2025. A provider can discuss whether the injection or the tablet fits you.
Can I get semaglutide online?
In states where care is available, a licensed provider can evaluate you by telehealth and, if appropriate, prescribe an FDA-approved semaglutide product filled by a licensed pharmacy.
Sources
- FDA-approved prescribing information: Wegovy (semaglutide) injection and tablets (DailyMed, NLM)
- Wilding JPH et al. Once-weekly semaglutide in adults with overweight or obesity (STEP 1). N Engl J Med 2021 (PubMed)
- FDA: Concerns with unapproved GLP-1 drugs used for weight loss
- NIH (NIDDK): Prescription medications to treat overweight and obesity
Sources are listed for reference and do not imply endorsement. Regulatory status can change; check the date above.
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